Jump to content

Vaccine Effectiveness


TukTuk
 Share

Recommended Posts

 

(CNN - 7.17.021) A head-to-head study of all three authorized coronavirus vaccines in the United States finds the Moderna vaccine is slightly more effective than Pfizer's in real-life use in keeping people out of the hospital, and Johnson & Johnson's Janssen vaccine comes in third, but still providing 71% protection.

Pfizer's vaccine provided 88% protection against hospitalization, and Moderna's was 93% effective.
 
The US Centers for Disease Control and Prevention led a nationwide study of vaccination involving more than 3,600 adults hospitalized for Covid-19 between March and August.
 

 

  • Like 1
Link to comment
Share on other sites

8 minutes ago, TukTuk said:

(CNN - 7.17.021) A head-to-head study of all three authorized coronavirus vaccines in the United States finds the Moderna vaccine is slightly more effective than Pfizer's in real-life use in keeping people out of the hospital, and Johnson & Johnson's Janssen vaccine comes in third, but still providing 71% protection.

Pfizer's vaccine provided 88% protection against hospitalization, and Moderna's was 93% effective.
 

 

Interesting, but 3600 subjects is a small study compared to total doses given and other available research.

Also it didn't specifically look at the delta variant that is causing most problems now, as the stated limitations of the study are:

The findings in this report are subject to at least six limitations. First, this analysis did not consider children, immunocompromised adults, or VE against COVID-19 that did not result in hospitalization. Second, the CIs for the Janssen VE estimates were wide because of the relatively small number of patients who received this vaccine. Third, follow-up time was limited to approximately 29 weeks since receipt of full vaccination, and further surveillance of VE over time is warranted. Fourth, although VE estimates were adjusted for relevant potential confounders, residual confounding is possible. Fifth, product-specific VE by variant, including against Delta variants (B.1.617.2 and AY sublineages), was not evaluated. Finally, antibody levels were measured at only a single time point 2–6 weeks after vaccination and changes in antibody response over time as well as cell-mediated immune responses were not assessed.

 

  • Like 2
Link to comment
Share on other sites

2 minutes ago, Bob20 said:

Interesting, but 3600 subjects is a small study compared to total doses given and other available research.

 

What do you mean "small study"? Wakefield based his evidence against the MMR vax re Autism on nine patients. And one of those had been diagnosed as autistic before being vaxxed!

How dare you. If 9 was good enough for Wakefield, then 3600 should satisfy your criteria (lol).

  • Haha 3
Link to comment
Share on other sites

24 minutes ago, TukTuk said:

(CNN - 7.17.021) A head-to-head study of all three authorized coronavirus vaccines in the United States finds the Moderna vaccine is slightly more effective than Pfizer's in real-life use in keeping people out of the hospital, and Johnson & Johnson's Janssen vaccine comes in third, but still providing 71% protection.

Pfizer's vaccine provided 88% protection against hospitalization, and Moderna's was 93% effective.
 
The US Centers for Disease Control and Prevention led a nationwide study of vaccination involving more than 3,600 adults hospitalized for Covid-19 between March and August.
 

Notice no mention of AZ vax. Is that in use in the US?

Edited by JohninDubin
  • Like 1
Link to comment
Share on other sites

2 minutes ago, JohninDubin said:

What do you mean "small study"? Wakefield based his evidence against the MMR vax re Autism on nine patients. And one of those had been diagnosed as autistic before being vaxxed!

How dare you. If 9 was good enough for Wakefield, then 3600 should satisfy your criteria (lol).

I thought it was 12? 🙄

  • Like 1
Link to comment
Share on other sites

3 minutes ago, JohninDubin said:

Notice no mention of AZ vax. Is that in use in the US.

No (they wanted to apply for approval Q3 2021, but not sure if they did), but they're thinking about buying Sinovac 🤣

  • Like 1
  • Haha 1
Link to comment
Share on other sites

2 minutes ago, Bob20 said:

I thought it was 12? 🙄

You could be right. I know it was a ludicrously small number and one of the cases involved a kid that was diagnosed prior to vaxxing. The British Medical Association which governs Doctor's conduct, deconstructed his entire methodology and described it as totally flawed. Later enquiries discovered that he had spent several years as a "paid expert" for a Solicitor who was trying to sue the NHS over the MMR vax, He earned over £400k for that.

Simultaneously to his attacking MMR, he was in the process of applying for a patent for a Measles Vax. Of course the question is then why would someone buy the single dose other than the "3-in-1". This was a man who clearly was not above conflicts of interest, with a total lack of candour in declaring these.

Link to comment
Share on other sites

5 hours ago, JohninDubin said:

You could be right. I know it was a ludicrously small number and one of the cases involved a kid that was diagnosed prior to vaxxing. The British Medical Association which governs Doctor's conduct, deconstructed his entire methodology and described it as totally flawed. Later enquiries discovered that he had spent several years as a "paid expert" for a Solicitor who was trying to sue the NHS over the MMR vax, He earned over £400k for that.

Simultaneously to his attacking MMR, he was in the process of applying for a patent for a Measles Vax. Of course the question is then why would someone buy the single dose other than the "3-in-1". This was a man who clearly was not above conflicts of interest, with a total lack of candour in declaring these.

Yes, I remember it well. Caused quite a stir in the media at the time and a lot of confusion for a lot of people, even today.

  • Like 2
Link to comment
Share on other sites

To determine actual vaccine effectiveness in real-life, probably the best and most comprehensive data are published fortnightly by PublicHealth England, in their Vaccine Surveillance Report.  Attached the recently issued week 37 report which provides insight in delta-variant infections, hospitalizations and deaths of the entire population of England for the period week 33 to 36 < 16 August till 12 September >. 

Attached below the four tables of interest:

image.thumb.png.b811c179e73506ef75ee69afba55a63d.png

image.thumb.png.87899341d1fd4c6ddfa254f8c819bced.png

image.thumb.png.f15404c9969b836a699ec096b0e2f5c4.png

image.thumb.png.110c4a3deadc7380298a90800837ff58.png

The full report can be downloaded here >  https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1018416/Vaccine_surveillance_report_-_week_37_v2.pdf

 

Link to comment
Share on other sites

7 hours ago, JohninDubin said:

Notice no mention of AZ vax. Is that in use in the US?

Not approved, but is manufactured in the US at the Emergent Biosolutions plant in Baltimore, Md. — and still in the U.S.— until it’s been tested further before the US will look at approving it,  It however, has been shipped to Canada, Mexico and many other nations.  Apparently the FDA was less than impressed with some quality control issues they saw and wanted more studies done.

However AZ is looking at gaining approval sometime this year

https://www.msn.com/en-us/news/politics/astrazeneca-to-seek-us-approval-for-covid-19-vaccine-by-second-half-of-2021/ar-AAMI4qI

Following U.S. trial data released in late March, AstraZeneca intended to seek authorization of its vaccine by mid-April, according to the AP. The company then decided to seek full approval of the vaccine instead of approval through an emergency use authorization. A biologics license application requires at least six months of data.

Edited by ThailandRyan
  • Like 1
Link to comment
Share on other sites

8 hours ago, JohninDubin said:

You could be right. I know it was a ludicrously small number and one of the cases involved a kid that was diagnosed prior to vaxxing. The British Medical Association which governs Doctor's conduct, deconstructed his entire methodology and described it as totally flawed. Later enquiries discovered that he had spent several years as a "paid expert" for a Solicitor who was trying to sue the NHS over the MMR vax, He earned over £400k for that.

Simultaneously to his attacking MMR, he was in the process of applying for a patent for a Measles Vax. Of course the question is then why would someone buy the single dose other than the "3-in-1". This was a man who clearly was not above conflicts of interest, with a total lack of candour in declaring these.

My daughter has informed me that the Japanese Health Authorities have ceased MMR in favour of separate shots. Perhaps in an attempt to distinguish any individual effects ?

  • Like 1
  • Thanks 1
Link to comment
Share on other sites

I have just googled that subject and discovered it happened  back in the early  90's as a direct result of the "autism" concerns. It seems that despite the change and removing mandatory vaccination for children the  autism rate has continued to rise in Japan!

Back to the drawing board I guess for those who wish to distract from all the other crap in processed foods being a more likely cause. IMO.

Link to comment
Share on other sites

3 hours ago, Convert54 said:

My daughter has informed me that the Japanese Health Authorities have ceased MMR in favour of separate shots. Perhaps in an attempt to distinguish any individual effects ?

That's interesting. Though there has never been any proof that MMR increases autism, people Sen Kennedy are still not satisfied, and he in particular, points out the vax contains Mercury, which is used as a preservative. On the face of it, that should be alarming until you understand that the human body contains mercury in concentrations many times greater than that found in the MMR Vax.

Of course the Japanese have a bad history with with mercury contamination (Minimata Disease), where thousands of Japanese were poisoned following a chemical plant pouring it's waste mercury into the sea. This was then absorbed by local fish, and the fish then eaten by locals.

Whether the Japanese will find anything through this study remains to be seen. There is a case for studying the effects of the combination and whether this might be the problem. I often think of salt, which is essential for life, but is made of two deadly poisons: Sodium and Chlorine. Is it possible that the combination of three vaccines has produced an unintended consequence. Who knows? 

Link to comment
Share on other sites

A couple of posts have been removed that were in reply to another post which provided no evidence or link to a comment.

Please read the forum rules

 

5. Understand that the Forum considers “Facts” to differ from a “Personal Opinion.” Facts may be inferred or quoted. Members are responsible to make sure their Posts are not misleading and do not knowingly share articles, pictures and videos previously identified as Misinformation.

6. All text and posted content, must align to the topic and/or the first post under that topic. Post must be accompanied by a personal comment & link (URL) to any source for verification.

 

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Unfortunately, your content contains terms that we do not allow. Please edit your content to remove the highlighted words below.
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

 Share

×
×
  • Create New...

Important Information

By posting on Thaiger Talk you agree to the Terms of Use