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Australians Confused


JTCarius
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What’s the official advice?

The evidence underpinning the recommended 12 week gap between the first and second AstraZeneca shots comes from a study published in the Lancet.

The study found leaving less than six weeks between the initial shot and the booster gave 55.1% efficacy (protection from symptomatic disease). Leaving 6-8 weeks between shots increased efficacy to 59.9%, and waiting 9-11 weeks, efficacy was 63.7%. However, if the gap was 12 weeks or longer efficacy jumped to 81.3%.

So to get the best protection from the AstraZeneca vaccine, you need at least 12 weeks between your first and second shot.

Retrieved from https://theconversation.com/should-i-have-my-astrazeneca-booster-shot-at-8-weeks-rather-than-12-heres-the-evidence-so-you-can-decide-164164

 

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"The analysis also showed the potential for the vaccine to reduce asymptomatic transmission of the virus, based on weekly swabs obtained from volunteers in the UK trial. The data showed that PCR positive readings were reduced by 67% (CI: 49%, 78%) after a single dose, and 50% (CI: 38% to 59%) after the two dose regimen, supporting a substantial impact on transmission of the virus."

Retrieved from https://www.astrazeneca.com/media-centre/press-releases/2021/covid-19-vaccine-astrazeneca-confirms-protection-against-severe-disease-hospitalisation-and-death-in-the-primary-analysis-of-phase-iii-trials.html

Edited by JTCarius
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"COVID-19 Vaccine AstraZeneca confirms 100% protection against severe disease, hospitalisation and death in the primary analysis of Phase III trials"

Retrieved from https://www.astrazeneca.com/media-centre/press-releases/2021/covid-19-vaccine-astrazeneca-confirms-protection-against-severe-disease-hospitalisation-and-death-in-the-primary-analysis-of-phase-iii-trials.html

 

 

I am getting depressed- JTCarius

Edited by JTCarius
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Just now, JamesE said:

I saw the topic title and thought: @JTCarius has been blessed with a keen sense of the obvious.

No I think more like excellent skills at Googling and then cutting and pasting. But that's fine 'cos if its "out there" why not read and share it ?

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1 hour ago, JTCarius said:

What’s the official advice?

The study found leaving less than six weeks between the initial shot and the booster gave 55.1% efficacy (protection from symptomatic disease). Leaving 6-8 weeks between shots increased efficacy to 59.9%, and waiting 9-11 weeks, efficacy was 63.7%. However, if the gap was 12 weeks or longer efficacy jumped to 81.3%.

So to get the best protection from the AstraZeneca vaccine, you need at least 12 weeks between your first and second shot.

...

So the longer you wait, the more 'protection' you get.  Cool, I gladly take that official advice and wait a life-time! ?

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Mrs was telling me of a Thai Dr from a major Bkk hospital claiming not much point in a 2nd jab as it only gives a small 2-3 % improvement over the first. I wonder why he might be claiming that!

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1 hour ago, thai3 said:

Mrs was telling me of a Thai Dr from a major Bkk hospital claiming not much point in a 2nd jab as it only gives a small 2-3 % improvement over the first. I wonder why he might be claiming that!

Because he's a THAI doctor?

  • Haha 2
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Our second vaccine dose was scheduled by the clinic - we had very little input. The good news is that it will be 12 weeks exactly after the first shots.  Seems they listened to JT ?

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18 hours ago, JTCarius said:

What’s the official advice?

The evidence underpinning the recommended 12 week gap between the first and second AstraZeneca shots comes from a study published in the Lancet.

The study found leaving less than six weeks between the initial shot and the booster gave 55.1% efficacy (protection from symptomatic disease). Leaving 6-8 weeks between shots increased efficacy to 59.9%, and waiting 9-11 weeks, efficacy was 63.7%. However, if the gap was 12 weeks or longer efficacy jumped to 81.3%.

So to get the best protection from the AstraZeneca vaccine, you need at least 12 weeks between your first and second shot.

Retrieved from https://theconversation.com/should-i-have-my-astrazeneca-booster-shot-at-8-weeks-rather-than-12-heres-the-evidence-so-you-can-decide-164164

The more astute observer (e.g., JamesE) will realize that this study is not peer-reviewed or subject to meta-analysis.

The Austrailian news outlet cited above indiscriminately referred to "..the Lancet".

The all-powerful Lancet. Abode to the overlords of medical truth. The truth that ye layman shall NOT apply discernment towards. 

The aformentioned study is from the Lancet pre-print server. 

The following link is from a February 2021 Time article and is an addendum to the previous article:

https://time.com/5936220/astrazeneca-vaccine-covid-19-spread/

I know we are all sick of reading endless walls of confusing, often contradicting information. 

The article is an easy read and I am specifically choosing to post information that I think is relevant to the members of this forum, expats in living in Thailand, Thai citizens and tourists entering Thailand who will likely take the AstraZenica shots several times. 

 

 

 

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7 hours ago, JTCarius said:

The more astute observer (e.g., JamesE) will realize that this study is not peer-reviewed or subject to meta-analysis.

The Austrailian news outlet cited above indiscriminately referred to "..the Lancet".

The all-powerful Lancet. Abode to the overlords of medical truth. The truth that ye layman shall NOT apply discernment towards. 

The aformentioned study is from the Lancet pre-print server. 

The following link is from a February 2021 Time article and is an addendum to the previous article:

https://time.com/5936220/astrazeneca-vaccine-covid-19-spread/

I know we are all sick of reading endless walls of confusing, often contradicting information. 

The article is an easy read and I am specifically choosing to post information that I think is relevant to the members of this forum, expats in living in Thailand, Thai citizens and tourists entering Thailand who will likely take the AstraZenica shots several times. 

 

Maybe next time you should check whether the paper is still at the preprint stage or finally peer-reviewed, which is true in this very case. That article was indeed published back in March:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00432-3/fulltext

 

 

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